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Determining the Isotonic solution in Sheep Erythrocytes Isotonic solution of red blood cells (Laboratory) red blood cell sizes in saline red blood cell expansion in salt
Date Submitted: 09/23/2000 18:14:11
Introduction
Every cell is selectively permeable to different molecules. This type of selectively is caused by a semi-permeable membrane, which allows the movement of certain molecules across it. Water exchange can be measured in two ways: RBC osmotic permeability is measured, and diffusional water permeability is measured (Benga and Borza 1995). Diffusion is the movement of high concentration to low concentration. The diffusion of water across a permeable membrane is called osmosis. Water concentration in red
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concentration saline in human blood is approximately 0.8% at isotonic state. The number of cells is a rough estimate relative to human RBC/ml because membrane permeability differs significantly from species to species (Benga and Borza 1995).
References
Benga G, Borza T. 1995. Diffusional water permeability of mammalian red blood cells. Comp. Biochem. Physiol. 112B(4):653-59.
Tuvia S, Levin S, Korenstein R. 1992. Correlation between local cell membrane displacements and filterability of human red blood cells. Eur. Biophys. 304(1):32-6.
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